Huntington's disease patients have selective problems with insight
Identifieur interne : 003398 ( Main/Exploration ); précédent : 003397; suivant : 003399Huntington's disease patients have selective problems with insight
Auteurs : Aileen K. Ho [Royaume-Uni] ; Anna O. G. Robbins [Royaume-Uni] ; Roger A. Barker [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-03.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Cognition, Cognition Disorders (diagnosis), Cognition Disorders (epidemiology), Depression (diagnosis), Depression (epidemiology), Female, Human, Humans, Huntington Disease (epidemiology), Huntington disease, Huntington's disease, Male, Middle Aged, Nervous system diseases, Neuropsychological Tests, Quality of Life (psychology), Questionnaires, Self regulation, Severity of Illness Index, Social Control, Informal, carers, cognition, dysexecutive syndrome, insight, self‐regulation.
- MESH :
- diagnosis : Cognition Disorders, Depression.
- epidemiology : Cognition Disorders, Depression, Huntington Disease.
- psychology : Quality of Life.
- Female, Humans, Male, Middle Aged, Neuropsychological Tests, Questionnaires, Severity of Illness Index, Social Control, Informal.
Abstract
The objective of this study was to determine insight in patients with Huntington's disease (HD) by contrasting patients' ability to rate their own behavior with their ability to rate a person other than themselves. HD patients and carers completed the Dysexecutive Questionnaire (DEX), rating themselves and each other at two time points. The temporal stability of these ratings was initially examined using these two time points since there is no published test–retest reliability of the DEX with this population to date. This was followed by a comparison of patients' self‐ratings and carer's independent ratings of patients by performing correlations with patients' disease variables, and an exploratory factor analysis was conducted on both sets of ratings. The DEX showed good test–retest reliability, with patients consistently and persistently underestimating the degree of their dysexecutive behavior, but not that of their carers. Patients' self‐ratings and carers' ratings of patients both showed that dysexecutive behavior in HD can be fractionated into three underlying components (Cognition, Self‐regulation, Insight), and the relative ranking of these factors was similar for both data sets. HD patients consistently underestimated the extent of only their own dysexecutive behaviors relative to carers' ratings by 26%, but were similar in ascribing ranks to the components of dysexecutive behavior. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20739
Affiliations:
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Le document en format XML
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Barker</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cambridge Centre for Brain Repair, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-03">2006-03</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="385">385</biblScope><biblScope unit="page" to="389">389</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">B2B878CB04641798C720C3DF190F6D1785AA1BF5</idno><idno type="DOI">10.1002/mds.20739</idno><idno type="ArticleID">MDS20739</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cognition</term><term>Cognition Disorders (diagnosis)</term><term>Cognition Disorders (epidemiology)</term><term>Depression (diagnosis)</term><term>Depression (epidemiology)</term><term>Female</term><term>Human</term><term>Humans</term><term>Huntington Disease (epidemiology)</term><term>Huntington disease</term><term>Huntington's disease</term><term>Male</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Neuropsychological Tests</term><term>Quality of Life (psychology)</term><term>Questionnaires</term><term>Self regulation</term><term>Severity of Illness Index</term><term>Social Control, Informal</term><term>carers</term><term>cognition</term><term>dysexecutive syndrome</term><term>insight</term><term>self‐regulation</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term><term>Depression</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cognition Disorders</term><term>Depression</term><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Questionnaires</term><term>Severity of Illness Index</term><term>Social Control, Informal</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Autorégulation</term><term>Chorée Huntington</term><term>Cognition</term><term>Homme</term><term>Système nerveux pathologie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The objective of this study was to determine insight in patients with Huntington's disease (HD) by contrasting patients' ability to rate their own behavior with their ability to rate a person other than themselves. HD patients and carers completed the Dysexecutive Questionnaire (DEX), rating themselves and each other at two time points. The temporal stability of these ratings was initially examined using these two time points since there is no published test–retest reliability of the DEX with this population to date. This was followed by a comparison of patients' self‐ratings and carer's independent ratings of patients by performing correlations with patients' disease variables, and an exploratory factor analysis was conducted on both sets of ratings. The DEX showed good test–retest reliability, with patients consistently and persistently underestimating the degree of their dysexecutive behavior, but not that of their carers. Patients' self‐ratings and carers' ratings of patients both showed that dysexecutive behavior in HD can be fractionated into three underlying components (Cognition, Self‐regulation, Insight), and the relative ranking of these factors was similar for both data sets. HD patients consistently underestimated the extent of only their own dysexecutive behaviors relative to carers' ratings by 26%, but were similar in ascribing ranks to the components of dysexecutive behavior. © 2005 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li></region><settlement><li>Cambridge</li></settlement><orgName><li>Université de Cambridge</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Ho, Aileen K" sort="Ho, Aileen K" uniqKey="Ho A" first="Aileen K." last="Ho">Aileen K. Ho</name></noRegion><name sortKey="Barker, Roger A" sort="Barker, Roger A" uniqKey="Barker R" first="Roger A." last="Barker">Roger A. Barker</name><name sortKey="Barker, Roger A" sort="Barker, Roger A" uniqKey="Barker R" first="Roger A." last="Barker">Roger A. Barker</name><name sortKey="Ho, Aileen K" sort="Ho, Aileen K" uniqKey="Ho A" first="Aileen K." last="Ho">Aileen K. Ho</name><name sortKey="Robbins, Anna O G" sort="Robbins, Anna O G" uniqKey="Robbins A" first="Anna O. G." last="Robbins">Anna O. G. Robbins</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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